20. Cocaine: The Vasculitis Mimic

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Cocaine-Induced Vasculitis

The use of cocaine continues to grow worldwide. One of the possible side-effects of cocaine is vasculitis. Two distinct vasculitic syndromes have been described due to cocaine. One is cocaine-induced midline destructive lesion, secondary to a direct vasoconstrictor effect of cocaine, inducing ischemic necrosis of the septal cartilage and perforation of the nasal septum, mimicking findings of gr...

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Cocaine-induced Churg-Strauss vasculitis.

A freebase cocaine-smoking woman developed relapsing fever, bronchoconstriction, arthralgias and weight loss. Pulmonary infiltrates, arthritis, microhaematuria, pruriginous skin rash and mononeuritis multiplex were later added to the clinical picture. Both skin and muscle biopsies showed eosinophilic angiitis. Improvement or worsening of her clinical picture repeatedly coincided with avoidance ...

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Levamisole tainted cocaine induced vasculitis

Levamisole has been implicated in the vasculitis and aganulocytosis. It has been pulled from the United States market for human use. Due to its euphoric and bulking properties, it has been . used as a bulking agent in cocaine. We hereby present a case of a 56-year-old Hispanic male, who developed vasculitis due to cocaine use adulterated with levamisole.

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Vasculitis in a cocaine user.

DESCRIPTION A 45-year-old woman was admitted for a painful purpuric rash on her cheeks, ears and legs, which began after a 3-day period of heavy crack cocaine use. She reported a similar rash 3 years ago and a skin biopsy at that time revealed thrombi in the small blood vessels. However, serological testing was not consistent with any specific known diagnosis and she was discharged when her ras...

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Differentiation of Cocaine-Induced Midline Destructive Lesions from ANCA-Associated Vasculitis

Introduction: Cocaine-induced midline destructive lesions (CIMDL) are complications of regular nasal cocaine inhalation. CIMDL can mimic systemic diseases with positive anti-neutrophil cytoplasmic antibodies (ANCA), such as granulomatosis with polyangiitis (GPA).   Case Report: In this article, we describe the case of a young woman who presented with nasal perforation induced by cocaine, al...

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ژورنال

عنوان ژورنال: Rheumatology

سال: 2014

ISSN: 1462-0332,1462-0324

DOI: 10.1093/rheumatology/keu096.020